Benjamin Bonavida, Ph.D


Dr. Bonavida is currently a Distinguished Research Professor, Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine at the University of California, Los Angeles (UCLA). His research career, thus far, has focused on basic immunochemistry and cancer immunobiology. His research investigations have ranged from the mechanisms of cell-mediated killing and sensitization of resistant tumor cells to chemo/immunotherapies, characterization of resistant factors in cancer cells, cell-signaling pathways mediated by therapeutic anti-cancer antibodies, and characterization of each of the gene products in the dysregulated NF-κB/Snail/YY1/RKIP/PTEN loop in many cancers that regulate cell survival, proliferation, invasion, metastasis, and resistance. He has also investigated the role of nitric oxide in cancer and its potential anti-tumor activity. Many of the above studies are centered on the clinical challenging features of cancer patients’ failure to respond to both conventional and targeted therapies. He has published extensively on the above research topics. He is currently Editor-in-Chief of Critical Reviews in Oncogenesis, the Series Editor for Resistance to Targeted Anti-Cancer Therapeutics published by Springer, and the Series Editor of the following three series: Chemotherapy-Sensitizing Agents for Cancer, Breaking Cancer Resistance to Therapeutic Antibodies, and Breaking Tolerance to Anti-Cancer Immunotherapy, published by Elsevier/Academic Press.

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